Direct acetoxylation and etherification of anilides using phenyliodine bis(trifluoroacetate).
نویسندگان
چکیده
Treatment of various anilides with 1.5 equiv. of phenyliodine bis(trifluoroacetate) (PIFA) and 1.0 equiv. of BF(3)·OEt(2) in AcOH at room temperature afforded the corresponding para-acetoxylated products with high regioselectivity. In addition, this reaction could be expanded to the etherification of anilides. In the presence of 2.0 equiv. of PIFA and 2.0 equiv. of BF(3)·OEt(2), the reaction of anilides with alcohols provided the corresponding para-etherified products in good yields.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 5 شماره
صفحات -
تاریخ انتشار 2011